Paper I ready · Paper II coming soon in Medha AI. Paper I: APPSC Paper I: General Studies & Mental Ability · Paper II: Chemistry or Pharmacy Coming soon
Full numbered syllabus: every topic, chapter and micro-topic (printable)
The common APPSC General Studies & Mental Ability paper: current events, AP-focused history and geography, polity, economy, environment, disaster management, reasoning and data analysis. One mark per question.
1. Current events
- Major current events and issues: international, national and Andhra Pradesh
2. General science
- General science and its applications in day-to-day life
- Contemporary developments in Science & Technology and Information Technology
3. History of India
- Social, economic, cultural and political aspects
- Focus on AP and the Indian National Movement
4. Geography
- Geography of India with focus on Andhra Pradesh
5. Polity and governance
- Constitutional issues
- Public policy and reforms
- e-Governance initiatives
6. Economy
- Indian economy and planning
7. Environment
- Sustainable development
- Environmental protection
8. Disaster management
- Vulnerability profile
- Prevention and mitigation strategies
- Remote sensing and GIS in assessment of disasters
9. Reasoning
- Logical reasoning, analytical ability and logical interpretation
10. Data analysis
- Tabulation and visual representation of data
- Summary statistics: mean, median, mode and variance
- Interpretation
Degree-standard Chemistry (inorganic, organic, physical) or Pharmacy (law, pharmacognosy, instrumental analysis, formulation, medicinal chemistry, pharmacology). Both syllabi name exact lists, such as eight metals for extraction and ten crude drugs.
Chemistry, Section A: Inorganic
- Atomic structure: Schrodinger wave equation, quantum numbers, radial and angular probability, shapes of orbitals; Aufbau, Hund's rule, Pauli principle
- Chemical periodicity: s, p, d, f blocks; trends in atomic and ionic radii, ionisation potential, electron affinity, electronegativity
- Chemical bonding: sigma and pi bonds, hydrogen and metallic bonds, bond order, VSEPR, hybridisation and shapes
- Oxidation numbers and balancing redox equations
- Acids and bases: Bronsted, Lewis, HSAB principle, substituent and solvent effects
- Hydrogen (ortho/para, heavy water); s and p block: inert pair effect, alkali metals in liquid ammonia, boric acid, diborane, carboranes, oxyacids of N, P, S, Cl, interhalogens, pseudohalogens, noble gas compounds
- d block and lanthanides: oxidation states, magnetism, colour, lanthanide contraction
- Extraction of Na, Mg, Al, Fe, Ni, Cu, Ag, Au
- Nuclear chemistry: mass defect, binding energy, fission, fusion, reactors, radioisotopes
- Coordination compounds: nomenclature, isomerism, theories, role in nature and medicine
- Pollution and its control: air, water and radioactive pollution
Chemistry, Section B: Organic
- Inductive, mesomeric and hyperconjugative effects; dipole moments; reaction intermediates (carbocations, carbanions, free radicals, carbenes)
- Aliphatic compounds: free radical halogenation, Baeyer strain theory, Markownikoff's rule, peroxide effect, 1,3-dipolar addition, polymerisation; alkyl halides to nitro compounds
- Stereochemistry: Fischer, Newman and sawhorse projections, R/S and D/L, meso, erythro/threo, E/Z, conformations of cyclohexane, stereochemistry of SN1, SN2, E1, E2
- Grignard reagents and alkyl lithium; diethyl malonate, ethyl acetoacetate, keto-enol tautomerism
- Aromaticity and Huckel's rule; electrophilic substitution, Friedel-Crafts; phenols, diazonium salts, benzyne
- Biomolecules: glucose structure, osazones, step-up/step-down of sugars; amino acids, zwitterions, isoelectric point; oils, fats, soaps, detergents
- UV, visible, IR and NMR spectroscopy of simple organic molecules
Chemistry, Section C: Physical
- Gaseous state: van der Waals and virial equations, critical phenomena, mean free path
- Thermodynamics: first law, Joule-Thomson effect, inversion temperature; second law, entropy, free energy, equilibrium constant
- Phase rule: water, sulphur, lead-silver, salt hydrates; Clausius-Clapeyron equation; distribution law
- Solutions: Raoult's and Henry's law, critical solution temperatures, fractional and steam distillation; colligative properties and molecular weights
- Electrochemistry: pH, buffers, indicators, Ostwald's dilution law, Kohlrausch law, transport number, Nernst equation, fuel cells, potentiometric titrations
- Chemical kinetics: first and second order rate equations, half-life, Arrhenius parameters, collision and transition state theory
- Photochemistry (quantum yield), catalysis (Michaelis-Menten), colloids, micelles and emulsions
Pharmacy, Part I
- History of pharmacy, code of ethics, posology; dispensing of mixtures, emulsions, powders and suppositories; incompatibilities
- Pharmacy Act; Drugs and Cosmetics Act and Rules; Drugs Price Control Order with amendments
- Sterilisation methods and sterility tests; vaccines, sera and antitoxins; manufacture of penicillin and streptomycin
- Classification, adulteration and evaluation of crude drugs
- Pharmacognosy of senna, digitalis, ispaghula, cinchona, cinnamon, rauwolfia, podophyllum, ergot, cod liver oil and gelatin
- Colorimetry, spectrophotometry, fluorimetry, gas chromatography and HPLC: principles, instruments, uses
Pharmacy, Part II
- Rheology (Newtonian and non-Newtonian), colloidal and interfacial phenomena, emulsions and suspensions
- Physicochemical, formulation and biological factors affecting drug absorption
- Formulation, technology and quality control of tablets, capsules, liquid orals, aerosols, creams, ointments, injectables and sustained-release products
- Medicinal chemistry (SAR, synthesis, nomenclature, uses): hypnotics and sedatives, tranquilisers, analgesics and antipyretics, anti-inflammatory drugs, diuretics, antihypertensives, chemotherapeutic agents
- Pharmacology: local anaesthetics, diuretics, hormones, hyperglycemic agents (as printed; hypoglycaemic drugs are the usual heading), antihistamines, CNS drugs, adrenergic and cholinergic drugs, cardiovascular agents
- Pharmacokinetic and pharmacodynamic drug interactions, teratogenicity, drug-induced diseases
Each wrong answer loses 1/3 of the marks for that question (G.O.Ms.No.235, 06/12/2016).
Each wrong answer costs 1/3 of the marks for that question.
APPSC Paper I syllabus · APPSC Paper I study notes